Gastro-oesophageal reflux and cough.
نویسندگان
چکیده
Gastro-oesophageal reflux, either singly or in association with postnasal drip and/or asthma is considered to be a cause of chronic cough. The amount and nature of gastro-oesophageal reflux however is often normal with acid suppression having very little, if any therapeutic effect in these patients. This review examines the challenges posed when exploring the reflux-cough link, and discusses the merits and limitations of the proposed mechanisms of reflux leading to cough.
منابع مشابه
GASTRO-OESOPHAGEAL REFLUX Weakly acidic reflux in patients with chronic unexplained cough during 24 hour pressure, pH, and impedance monitoring
Background and aims: Acid gastro-oesophageal reflux is one of the most important causes of chronic cough. The response to acid suppression in these patients is not as good as in patients with heartburn but improvement with antireflux surgery has been reported, suggesting the involvement of a non-acidic gastric component in the refluxate. Less acidic reflux may produce symptoms such as regurgita...
متن کاملCough. 3: chronic cough and gastro-oesophageal reflux.
The pathogenesis and clinical features of gastro-oesophageal reflux related cough are complex and the diagnostic tests available are of limited reliability. Treatment needs to be tailored to the specific needs of individual patients and other possible causes of chronic cough should be investigated. Treatment should only be considered to have failed when cough persists after administration of pr...
متن کاملWeakly acidic reflux in patients with chronic unexplained cough during 24 hour pressure, pH, and impedance monitoring.
BACKGROUND AND AIMS Acid gastro-oesophageal reflux is one of the most important causes of chronic cough. The response to acid suppression in these patients is not as good as in patients with heartburn but improvement with antireflux surgery has been reported, suggesting the involvement of a non-acidic gastric component in the refluxate. Less acidic reflux may produce symptoms such as regurgitat...
متن کاملAbnormal oesophageal motility in patients with chronic cough.
BACKGROUND Although gastro-oesophageal reflux is a recognised cause of chronic cough, the role of oesophageal dysmotility is unknown. The aim of this study was to determine the prevalence of abnormal oesophageal motility in a selected group of patients with chronic cough. METHODS Oesophageal manometry and 24 hour pH monitoring were performed in 43 patients with chronic cough, 34 of whom had s...
متن کاملGastro-oesophageal reflux related cough and its response to laparoscopic fundoplication.
BACKGROUND This study was designed to determine prospectively the rate of cough before and after laparoscopic Nissen fundoplication performed for the control of gastro-oesophageal reflux disease. METHODS One hundred and ninety five consecutive patients (76 men) of mean (SD) age 46.9 (14.1) years with proven gastro-oesophageal reflux disease, who were either on long term omeprazole (n = 187) o...
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ورودعنوان ژورنال:
- The Journal of the Association of Physicians of India
دوره 61 5 Suppl شماره
صفحات -
تاریخ انتشار 2013